Forensic Toxicology: Biological Sampling and use of Different Analytical Techniques

Ninhydrin-based Forensic Investigations: Ii. Cyanide Analytical Toxicology

Recently, a novel ninhydrin reaction with cyanide has opened new ways to detect this poison in the body fluids and the environmental samples. Mainly, detection of cyanide with ninhydrin at a crime scene could be of prime interest for forensic investigators. Besides, the reaction conditions are very common, except the need to avoid oxygen and oxidizers. The ninhydrin-based assay proved to be hig...

Forensic toxicology.

Forensic toxicology is a discipline of analytical toxicology dedicated to toxicological problems of forensic relevance, for example driving under the influence of alcohol or drugs, or postmortem toxicology. High-quality analytical methods for identification and quantification of drugs, poisons, and/or their metabolites in complex matrices, for example body fluids or hair, are very important in ...

Use of ethyl glucuronide and ethyl sulphate in forensic toxicology

Forensic Medicine and Toxicology

Accident and suicide are the two main epidemiological categories of poisoning; at home and at work are the two main places for it to occur; and clinically it may conveniently be classed as acute or chronic. Availability plays an important part in the incidence of poisoning and in the choice of agent by a person intending suicide, in the substance swallowed by a child, and in the toxic agent aff...

Pharmacogenetics and forensic toxicology.

Large inter-individual variability in drug response and toxicity, as well as in drug concentrations after application of the same dosage, can be of genetic, physiological, pathophysiological, or environmental origin. Absorption, distribution and metabolism of a drug and interactions with its target often are determined by genetic differences. Pharmacokinetic and pharmacodynamic variations can a...